I have two awesome friends from High school Mary Giles and her husband Aaron Giles, who can use prayer for their little boy. Here is their story. These kids and my husband are my world and the Rare Disease Awareness It Starts With A Wish It Can End With A Cure Shirt. Our everyday normal was interrupted when Nicholas was diagnosed with Juvenile Dermatomyositis at the end of July. JDM is a rare autoimmune inflammatory disease of the muscle, skin, and blood vessels that affects about three in one million children each year. The cause is unknown. The primary symptoms of JDM include muscle weakness and skin rash. All age and ethnic groups are affected. Most cases start in children ages 5–10 and adults ages 40–50. Girls are affected about twice as often as boys.